QB: Peyton Manning serves as the no-brainer pick of the week. While you should start him anyway, you have to feel good going against the woeful Houston Texans, especially considering what Donovan McNabb did to them last week (314 yards and 3 td's).
On the flip side, I also like David Carr against the Colts. The Giants pulled a lot of boneheaded blunders that lost them the game against the Colts last week. If the Texans can keep the blunders to a minimum, expect a fun game of pinball between these two offenses.
RB: If Shaun Alexander cannot run on the Cardinals, he should retire. The Cards made Frank Gore look like Marshall Faulk last week.
Was the Panther defense last week that bad, or was the Falcon running game that good? We will find out this week when Chester Taylor of the Vikings gets a crack at the Panthers. With LB Dan Morgan out for the Panthers, Taylor looks like an even better play.
WR: Along with the Manning no-brainer above, I have to also include Marvin Harrison and Reggie Wayne. Throw in Andre Johnson and Eric Moulds for the full Colts-Texans list of receivers to play.
TE: Repeat after me: Antonio Gates, Antonio Gates, Antonio Gates...
Seriously, Gates should put up some better numbers against the woeful Titans this week.
The Todd Heap/Daniel Wilcox two-headed tight end monster in Baltimore should have a walk-through over the Raiders this week.
K: Considering what Jeff Wilkins of the Rams did to the Broncos last week, you have to like Lawrence Tynes of the Chiefs this week. As long as Jake Plummer is playing QB for the Broncos, their opponents should have plenty of oppurtunities in field goal range.
Shayne Graham of the Bengals should also have a solid week against the Browns.
DEFENSE/SPECIAL TEAMS: You have to love the Saints defense/special teams this week for two reasons. First, they get to feast at the Brett Favre buffet. Second, Reggie Bush returning punts.
Do I even need to suggest taking the Ravens against the Raiders? Jerry Porter should be laughing it up again this week.